There are 12 Trophies that can be earned in this title.

Bronze

Say Hi to the Nice People, Charlie
Throw your voice to every available target.

Curse the Luck
Get zapped with fewer than six Mole Curses.

Nine Lives of Sameth & Maximus
See Sameth and/or Maximus die at nine distinct points in the game.

Chrono Logic
Complete the four reels in sequential order.

Doppel Fluch
Cause German train passenger to be saddled with two curses at the same time.

Double-Crossed
Cause your little buddy to lose both his luck and his rabbithood at the same time.

Secret Handshake
Fool a Yog Soggoth devotee into thinking you’re a member of the Brotherhood.

Silver

Challenge of the Sphunx
Completed Monsieur Papierwaite's challenge

Looters of the Lost Toybox
Successfully raided the Tomb of Sammun-Mak.

Mystery on the Disorient Express
Foiled an onboard sneak-thief.

Open Wide
Make it through the Mouth of the Sphunx the first time it opens.

Gold

Horror Show
Stop a seriously sinister ceremony.

http://www.ps3trophies.org/game/sam-and-max-the-devils-playhouse-ep2/trophies/