It would take 3 playthroughs without using a manual save. I did 2 playthroughs, first one pretty much main story only. Quite an easy platinum though. I managed all the trophies during normal gameplay and without internet help except the last one.
My progression is going really well despite hitting a few bugs along the way but thank feck for manual saves!
I have completed 2 Factions and only have one left for the third ending then just mop up misc and collect the remaining bobbleheads for the Platinum.
But will make my Sanctuary a kick ass look xD
I’ve just found another workshop taking my total to 27. Not sure how many there are in the game but I think I must have them all now. Are you gonna post up a video walkthrough of Sanctuary when you’ve finished it Del?